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Accurate positioning of functional residues with robotics-inspired computational protein design
Proteins achieve their complex functions, such as molecular recognition with high affinity and specificity, through intricate three-dimensional geometries in functional sites. To engineer new protein functions, accurate positioning of amino acid functional groups is therefore critical but has remain...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931229/ https://www.ncbi.nlm.nih.gov/pubmed/35254891 http://dx.doi.org/10.1073/pnas.2115480119 |