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The UVSSA protein is part of a genome integrity homeostasis network with links to transcription-coupled DNA repair and ATM signaling

The UVSSA (KIAA1530) protein is a component of transcription-coupled repair which, together with the CSA(ERCC8) and CSB(ERCC6) proteins cooperates to relieve transcription-blocking DNA damage. Mutations in CSA and CSB are found in Cockayne syndrome (CS), which is a human recessively inherited photos...

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Detalles Bibliográficos
Autores principales: Kordon, Magdalena M., Arron, Sarah, Cleaver, James E., Bezrookove, Vladimir, Karentz, Deneb, Lu, Brian, Perr, Eli, Chang, Darwin, Pederson, Thoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931232/
https://www.ncbi.nlm.nih.gov/pubmed/35254895
http://dx.doi.org/10.1073/pnas.2116254119