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Modeling protein dynamics in Caenorhabditis elegans embryos reveals that the PLK-1 gradient relies on weakly coupled reaction–diffusion mechanisms

Protein gradients have fundamental roles in cell and developmental biology. In the one-cell Caenorhabditis elegans embryo, the mitotic Polo-Like Kinase 1 (PLK-1) forms an anterior-rich cytoplasmic gradient, which is crucial for asymmetric cell division and embryonic development. The PLK-1 gradient d...

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Detalles Bibliográficos
Autores principales: Barbieri, Sofia, Nurni Ravi, Aparna, Griffin, Erik E., Gotta, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931239/
https://www.ncbi.nlm.nih.gov/pubmed/35259017
http://dx.doi.org/10.1073/pnas.2114205119