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Remodeling Yersinia pseudotuberculosis to generate a highly immunogenic outer membrane vesicle vaccine against pneumonic plague

A recombinant enteric Yersinia pseudotuberculosis PB1(+) strain (Yptb) was designed to synthesize an adjuvant form of lipid A (monophosphoryl lipid A [MPLA]), and tailor an Asd(+) plasmid pSMV13 for high synthesis of the Yersinia pestis LcrV antigen. The recombinant Yptb mutant harboring the pSMV13...

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Detalles Bibliográficos
Autores principales:	Wang, Xiuran, Li, Peng, Singh, Amit K., Zhang, Xiangmin, Guan, Ziqiang, Curtiss, Roy, Sun, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931243/ https://www.ncbi.nlm.nih.gov/pubmed/35275791 http://dx.doi.org/10.1073/pnas.2109667119

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