A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum

Astrocytes in the adult brain show cellular plasticity; however, whether they have the potential to generate multiple lineages remains unclear. Here, we perform in vivo screens and identify DLX2 as a transcription factor that can unleash the multipotentiality of adult resident astrocytes. Genetic li...

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Detalles Bibliográficos
Autores principales: Zhang, Yunjia, Li, Boxun, Cananzi, Sergio, Han, Chuanhui, Wang, Lei-Lei, Zou, Yuhua, Fu, Yang-Xin, Hon, Gary C., Zhang, Chun-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931246/
https://www.ncbi.nlm.nih.gov/pubmed/35254903
http://dx.doi.org/10.1073/pnas.2107339119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931246/
https://www.ncbi.nlm.nih.gov/pubmed/35254903
http://dx.doi.org/10.1073/pnas.2107339119

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