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Using single-cell models to predict the functionality of synthetic circuits at the population scale

Mathematical modeling has become a major tool to guide the characterization and synthetic construction of cellular processes. However, models typically lose their capacity to explain or predict experimental outcomes as soon as any, even minor, modification of the studied system or its operating cond...

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Detalles Bibliográficos
Autores principales: Aditya, Chetan, Bertaux, François, Batt, Gregory, Ruess, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931247/
https://www.ncbi.nlm.nih.gov/pubmed/35271387
http://dx.doi.org/10.1073/pnas.2114438119