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Fertilization, Oocyte Activation, Calcium Release and Epigenetic Remodelling: Lessons From Cancer Models

Oocyte activation deficiency (OAD) is the basis of Total Fertilisation Failure (TFF) and is attributed to mutations in the PLCζ gene—termed male factor infertility. This derives abnormal Ca(2+) oscillations and could be the main cause of primary disruptions in the gene expression of Ca(2+)-related p...

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Detalles Bibliográficos
Autores principales: Shafqat, Areez, Kashir, Junaid, Alsalameh, Sulaiman, Alkattan, Khaled, Yaqinuddin, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931327/
https://www.ncbi.nlm.nih.gov/pubmed/35309905
http://dx.doi.org/10.3389/fcell.2022.781953