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Fertilization, Oocyte Activation, Calcium Release and Epigenetic Remodelling: Lessons From Cancer Models
Oocyte activation deficiency (OAD) is the basis of Total Fertilisation Failure (TFF) and is attributed to mutations in the PLCζ gene—termed male factor infertility. This derives abnormal Ca(2+) oscillations and could be the main cause of primary disruptions in the gene expression of Ca(2+)-related p...
Autores principales: | Shafqat, Areez, Kashir, Junaid, Alsalameh, Sulaiman, Alkattan, Khaled, Yaqinuddin, Ahmed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931327/ https://www.ncbi.nlm.nih.gov/pubmed/35309905 http://dx.doi.org/10.3389/fcell.2022.781953 |
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