Cargando…
Species-specific KRAB-ZFPs function as repressors of retroviruses by targeting PBS regions
Eukaryotic genomes harbor sequences derived from the chromosomal integration of ancient viruses, such as endogenous retroviruses (ERVs), which comprise 8% of the human genome. Like exogenous retroviruses, ERVs retain many common functional elements, including the corresponding DNA sequences of trans...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931336/ https://www.ncbi.nlm.nih.gov/pubmed/35259018 http://dx.doi.org/10.1073/pnas.2119415119 |