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Species-specific KRAB-ZFPs function as repressors of retroviruses by targeting PBS regions

Eukaryotic genomes harbor sequences derived from the chromosomal integration of ancient viruses, such as endogenous retroviruses (ERVs), which comprise 8% of the human genome. Like exogenous retroviruses, ERVs retain many common functional elements, including the corresponding DNA sequences of trans...

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Detalles Bibliográficos
Autores principales: Yang, Bo, Fang, Lu, Gao, Qianqian, Xu, Ce, Xu, Junqin, Chen, Zhen-Xia, Wang, Yixuan, Yang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931336/
https://www.ncbi.nlm.nih.gov/pubmed/35259018
http://dx.doi.org/10.1073/pnas.2119415119