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Species-specific KRAB-ZFPs function as repressors of retroviruses by targeting PBS regions
Eukaryotic genomes harbor sequences derived from the chromosomal integration of ancient viruses, such as endogenous retroviruses (ERVs), which comprise 8% of the human genome. Like exogenous retroviruses, ERVs retain many common functional elements, including the corresponding DNA sequences of trans...
Autores principales: | Yang, Bo, Fang, Lu, Gao, Qianqian, Xu, Ce, Xu, Junqin, Chen, Zhen-Xia, Wang, Yixuan, Yang, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931336/ https://www.ncbi.nlm.nih.gov/pubmed/35259018 http://dx.doi.org/10.1073/pnas.2119415119 |
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