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Genome-Wide Analysis for the Regulation of Gene Alternative Splicing by DNA Methylation Level in Glioma and its Prognostic Implications

Glioma is a primary high malignant intracranial tumor with poorly understood molecular mechanisms. Previous studies found that both DNA methylation modification and gene alternative splicing (AS) play a key role in tumorigenesis of glioma, and there is an obvious regulatory relationship between them...

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Detalles Bibliográficos
Autores principales: Yang, Zeyuan, He, Yijie, Wang, Yongheng, Huang, Lin, Tang, Yaqin, He, Yue, Chen, Yihan, Han, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931337/
https://www.ncbi.nlm.nih.gov/pubmed/35309147
http://dx.doi.org/10.3389/fgene.2022.799913