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Myc Supports Self-Renewal of Basal Cells in the Esophageal Epithelium

It is widely believed that cellular senescence plays a critical role in both aging and cancer, and that senescence is a fundamental, permanent growth arrest that somatic cells cannot avoid. Here we show that Myc plays an important role in self-renewal of esophageal epithelial cells, contributing to...

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Detalles Bibliográficos
Autores principales: Hishida, Tomoaki, Vazquez-Ferrer, Eric, Hishida-Nozaki, Yuriko, Takemoto, Yuto, Hatanaka, Fumiyuki, Yoshida, Kei, Prieto, Javier, Sahu, Sanjeeb Kumar, Takahashi, Yuta, Reddy, Pradeep, O’Keefe, David D., Rodriguez Esteban, Concepcion, Knoepfler, Paul S., Nuñez Delicado, Estrella, Castells, Antoni, Campistol, Josep M., Kato, Ryuji, Nakagawa, Hiroshi, Izpisua Belmonte, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931341/
https://www.ncbi.nlm.nih.gov/pubmed/35309931
http://dx.doi.org/10.3389/fcell.2022.786031