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Ferroptosis regulation by the NGLY1/NFE2L1 pathway

Ferroptosis is an oxidative form of nonapoptotic cell death whose transcriptional regulation is poorly understood. Cap’n’collar (CNC) transcription factors including nuclear factor erythroid-2–related factor 1 (NFE2L1/NRF1) and NFE2L2 (NRF2) are important regulators of oxidative stress responses. NF...

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Detalles Bibliográficos
Autores principales:	Forcina, Giovanni C., Pope, Lauren, Murray, Magdalena, Dong, Wentao, Abu-Remaileh, Monther, Bertozzi, Carolyn R., Dixon, Scott J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931371/ https://www.ncbi.nlm.nih.gov/pubmed/35271393 http://dx.doi.org/10.1073/pnas.2118646119

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