The C terminus of the mycobacterium ESX-1 secretion system substrate ESAT-6 is required for phagosomal membrane damage and virulence

Mycobacterium tuberculosis and its close relative Mycobacterium marinum infect macrophages and induce the formation of granulomas, organized macrophage-rich immune aggregates. These mycobacterial pathogens can accelerate and co-opt granuloma formation for their benefit, using the specialized secreti...

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Detalles Bibliográficos
Autores principales: Osman, Morwan M., Shanahan, Jonathan K., Chu, Frances, Takaki, Kevin K., Pinckert, Malte L., Pagán, Antonio J., Brosch, Roland, Conrad, William H., Ramakrishnan, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931374/
https://www.ncbi.nlm.nih.gov/pubmed/35271388
http://dx.doi.org/10.1073/pnas.2122161119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931374/
https://www.ncbi.nlm.nih.gov/pubmed/35271388
http://dx.doi.org/10.1073/pnas.2122161119

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