Protocol to assess the effect of disease-driving variants on mouse brain morphology and primary hippocampal neurons

Genetic variants that affect neurological function will often produce changes visible at the level of gross morphology, either of the whole brain or of specific neuronal types. Here we describe how to perfuse and dissect the brain in preparation for Nissl staining. Then we outline steps for culturin...

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Detalles Bibliográficos
Autores principales: de Prisco, Nicola, Chemiakine, Alexei, Lee, Winston, Botta, Salvatore, Gennarino, Vincenzo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931472/
https://www.ncbi.nlm.nih.gov/pubmed/35310074
http://dx.doi.org/10.1016/j.xpro.2022.101244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931472/
https://www.ncbi.nlm.nih.gov/pubmed/35310074
http://dx.doi.org/10.1016/j.xpro.2022.101244

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