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Immunotherapy for a POLE Mutation Advanced Non-Small-Cell Lung Cancer Patient

Currently, the predictive role of POLE mutations for immunotherapy is under intense investigation. The POLE gene encodes one of the four subunits of DNA polymerase important for DNA replication and repair. POLE mutations are related to other favorable predicative factors such as high expression of P...

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Detalles Bibliográficos
Autores principales: Fu, Yang, Zheng, Yue, Wang, Pei-Pei, Chen, Yue-Yun, Ding, Zhen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931479/
https://www.ncbi.nlm.nih.gov/pubmed/35308232
http://dx.doi.org/10.3389/fphar.2022.817265