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Simulation Modeling of Reduced Glycosylation Effects on Potassium Channels of Mouse Cardiomyocytes

Dilated cardiomyopathy (DCM) is the third most common cause of heart failure and the primary reason for heart transplantation; upward of 70% of DCM cases are considered idiopathic. Our in-vitro experiments showed that reduced hybrid/complex N-glycosylation in mouse cardiomyocytes is linked with DCM....

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Detalles Bibliográficos
Autores principales: Kim, Haedong, Yang, Hui, Ednie, Andrew R., Bennett, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931503/
https://www.ncbi.nlm.nih.gov/pubmed/35309072
http://dx.doi.org/10.3389/fphys.2022.816651