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Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration
Cell migration is a complex process that involves coordinated changes in membrane transport and actin cytoskeleton dynamics. Ras-like small monomeric GTPases, such as Rap2, play a key role in regulating actin cytoskeleton dynamics and cell adhesions. However, how Rap2 function, localization, and act...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931537/ https://www.ncbi.nlm.nih.gov/pubmed/35293963 http://dx.doi.org/10.1083/jcb.202107114 |