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Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration

Cell migration is a complex process that involves coordinated changes in membrane transport and actin cytoskeleton dynamics. Ras-like small monomeric GTPases, such as Rap2, play a key role in regulating actin cytoskeleton dynamics and cell adhesions. However, how Rap2 function, localization, and act...

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Detalles Bibliográficos
Autores principales: Duncan, Emily D., Han, Ke-Jun, Trout, Margaret A., Prekeris, Rytis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931537/
https://www.ncbi.nlm.nih.gov/pubmed/35293963
http://dx.doi.org/10.1083/jcb.202107114