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Inhibition of PI3K/AKT/mTOR Signalling Pathway Activates Autophagy and Suppresses Peritoneal Fibrosis in the Process of Peritoneal Dialysis

Peritoneal dialysis (PD) is an important part of replacement therapy for kidney failure. However, long-term PD treatment can cause peritoneal fibrosis. Autophagy may be involved in the pathological mechanism of peritoneal fibrosis (PF). Although autophagy is currently known to be involved in course...

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Detalles Bibliográficos
Autores principales: Jia, Miao, Qiu, Hong, Lin, Lihua, Zhang, Shun, Li, Damei, Jin, Donghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931542/
https://www.ncbi.nlm.nih.gov/pubmed/35309056
http://dx.doi.org/10.3389/fphys.2022.778479