The use of Sonidegib in the adjuvant and advanced phases of Sonic Hedge Hog Mutant Medulloblastomas

Medulloblastomas are rare embryonal primary brain tumours originating in the cerebellum. Most medulloblastomas arising in adults are associated with mutations in the Sonic Hedge Hog (SHH) pathway. Patient 1 was prescribed Sonidegib for recurrent metastatic SHH mutated medulloblastoma multiple lines...

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Detalles Bibliográficos
Autores principales: Yuile, Alexander K, Kastelan, Marina, Lee, Adrian PS, Back, Michael, Drummond, James, Wheeler, Helen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931813/
https://www.ncbi.nlm.nih.gov/pubmed/35316996
http://dx.doi.org/10.1093/omcr/omac019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931813/
https://www.ncbi.nlm.nih.gov/pubmed/35316996
http://dx.doi.org/10.1093/omcr/omac019

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