Localized delivery of brain-derived neurotrophic factor from PLGA microspheres promotes peripheral nerve regeneration in rats

BACKGROUND: Repair of peripheral nerve defect presents a considerable challenge for reconstructive surgeons. The aim of this study is to develop a brain-derived neurotrophic factor (BDNF) from poly(D,L-lactide-co-glycolide) (PLGA) microspheres for the treatment of the peripheral nerve defect. METHOD...

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Detalles Bibliográficos
Autores principales: Shi, Zheng-liang, Fan, Zhi-yong, Zhang, Hua, Li, Shen-tai, Yuan, He, Tong, Jiu-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931983/
https://www.ncbi.nlm.nih.gov/pubmed/35303915
http://dx.doi.org/10.1186/s13018-022-02985-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931983/
https://www.ncbi.nlm.nih.gov/pubmed/35303915
http://dx.doi.org/10.1186/s13018-022-02985-x

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