Cargando…

Localized delivery of brain-derived neurotrophic factor from PLGA microspheres promotes peripheral nerve regeneration in rats

BACKGROUND: Repair of peripheral nerve defect presents a considerable challenge for reconstructive surgeons. The aim of this study is to develop a brain-derived neurotrophic factor (BDNF) from poly(D,L-lactide-co-glycolide) (PLGA) microspheres for the treatment of the peripheral nerve defect. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Zheng-liang, Fan, Zhi-yong, Zhang, Hua, Li, Shen-tai, Yuan, He, Tong, Jiu-hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931983/ https://www.ncbi.nlm.nih.gov/pubmed/35303915 http://dx.doi.org/10.1186/s13018-022-02985-x

Ejemplares similares

Localized and Sustained Delivery of Erythropoietin from PLGA Microspheres Promotes Functional Recovery and Nerve Regeneration in Peripheral Nerve Injury
por: Zhang, Wei, et al.
Publicado: (2015)

Erratum to “Localized and Sustained Delivery of Erythropoietin from PLGA Microspheres Promotes Functional Recovery and Nerve Regeneration in Peripheral Nerve Injury”
por: Zhang, Wei, et al.
Publicado: (2015)

Local delivery of controlled-release simvastatin/PLGA/HAp microspheres enhances bone repair
por: Tai, I-Chun, et al.
Publicado: (2013)

PERIPHERAL NERVE REGENERATION: CELL THERAPY AND NEUROTROPHIC FACTORS
por: Sebben, Alessandra Deise, et al.
Publicado: (2015)

Preparation of PLGA Nanoparticles by Milling Spongelike PLGA Microspheres
por: Lee, Jimin, et al.
Publicado: (2022)

Development of Risperidone PLGA Microspheres
por: D'Souza, Susan, et al.
Publicado: (2014)

Cartilage Extracellular Matrix Scaffold With Kartogenin-Encapsulated PLGA Microspheres for Cartilage Regeneration
por: Zhao, Yanhong, et al.
Publicado: (2020)

Erythropoietin-PLGA-PEG as a local treatment to promote functional recovery and neurovascular regeneration after peripheral nerve injury
por: Manto, Kristen M., et al.
Publicado: (2022)

Local administration of icariin contributes to peripheral nerve regeneration and functional recovery
por: Chen, Bo, et al.
Publicado: (2015)

Neurotrophic factors and corneal nerve regeneration
por: Sacchetti, Marta, et al.
Publicado: (2017)

The balanced microenvironment regulated by the degradants of appropriate PLGA scaffolds and chitosan conduit promotes peripheral nerve regeneration
por: Lu, Panjian, et al.
Publicado: (2021)

Assessment of Residual Solvent and Drug in PLGA Microspheres by Derivative Thermogravimetry
por: Shim, Hyunjin, et al.
Publicado: (2020)

Polyaniline promotes peripheral nerve regeneration by enhancement of the brain-derived neurotrophic factor and ciliary neurotrophic factor expression and activation of the ERK1/2/MAPK signaling pathway
por: Fan, Lin, et al.
Publicado: (2017)

Local retention efficacy of steroid-loaded PLGA microspheres in epidural injection
por: Jang, Sowon, et al.
Publicado: (2022)

Electroacupuncture promotes peripheral nerve regeneration after facial nerve crush injury and upregulates the expression of glial cell-derived neurotrophic factor
por: Fei, Jing, et al.
Publicado: (2019)

Drug-Loaded PLGA Electrospraying Porous Microspheres for the Local Therapy of Primary Lung Cancer via Pulmonary Delivery
por: Zhu, Lifei, et al.
Publicado: (2017)

Protein Loading into Spongelike PLGA Microspheres
por: Kim, Yuyoung, et al.
Publicado: (2021)

Sustained delivery of 17β-estradiol by human amniotic extracellular matrix (HAECM) scaffold integrated with PLGA microspheres for endometrium regeneration
por: Chen, Yue, et al.
Publicado: (2020)

PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application
por: Su, Yue, et al.
Publicado: (2021)

Rationalized design to explore the full potential of PLGA microspheres as drug delivery systems
por: Martinez-Borrajo, Rebeca, et al.
Publicado: (2023)

PLGA Microspheres Incorporated Gelatin Scaffold: Microspheres Modulate Scaffold Properties
por: Banerjee, Indranil, et al.
Publicado: (2009)

The Role of Neurotrophic Factors Conjugated to Iron Oxide Nanoparticles in Peripheral Nerve Regeneration: In Vitro Studies
por: Ziv-Polat, Ofra, et al.
Publicado: (2014)

Dexamethasone and vitamin B(12) synergistically promote peripheral nerve regeneration in rats by upregulating the expression of brain-derived neurotrophic factor
por: Sun, Hongzhi, et al.
Publicado: (2012)

Territory maximization hypothesis during peripheral nerve regeneration
por: Deng, Jiu-xu, et al.
Publicado: (2018)

Uniform-sized insulin-loaded PLGA microspheres for improved early-stage peri-implant bone regeneration
por: Wang, Xing, et al.
Publicado: (2019)

Microfluidic synthesis of PLGA/carbon quantum dot microspheres for vascular endothelial growth factor delivery
por: Omidi, Meisam, et al.
Publicado: (2019)

Paclitaxel-loaded PLGA microspheres with a novel morphology to facilitate drug delivery and antitumor efficiency
por: Zhang, Zongrui, et al.
Publicado: (2018)

Heuristic modeling of macromolecule release from PLGA microspheres
por: Szlęk, Jakub, et al.
Publicado: (2013)

In Vitro and In Vivo Evaluations of PLGA Microspheres Containing Nalmefene
por: Xie, Xiangyang, et al.
Publicado: (2015)

Insulin-loaded PLGA microspheres for glucose-responsive release
por: Wu, Jun-Zi, et al.
Publicado: (2017)

Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons
por: He, Qian-Ru, et al.
Publicado: (2022)

Salidroside promotes peripheral nerve regeneration based on tissue engineering strategy using Schwann cells and PLGA: in vitro and in vivo
por: Liu, Hui, et al.
Publicado: (2017)

Light enhanced bone regeneration in an athymic nude mouse implanted with mesenchymal stem cells embedded in PLGA microspheres
por: Park, Ji Sun, et al.
Publicado: (2016)

Brain-derived neurotrophic factor modulates immune reaction in mice with peripheral nerve xenotransplantation
por: Yu, Xin, et al.
Publicado: (2016)

Peripheral Regulation of Central Brain-Derived Neurotrophic Factor Expression through the Vagus Nerve
por: Amagase, Yoko, et al.
Publicado: (2023)

CRISPR-based Activation of Endogenous Neurotrophic Genes in Adipose Stem Cell Sheets to Stimulate Peripheral Nerve Regeneration
por: Hsu, Mu-Nung, et al.
Publicado: (2019)

Delivery of Wnt inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush
por: Zhang, Na, et al.
Publicado: (2022)

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration
Publicado: (1992)

Nerve‐on‐a‐Chip Derived Biomimicking Microfibers for Peripheral Nerve Regeneration
por: Yu, Yunru, et al.
Publicado: (2023)

Process analytical technology as in-process control tool in semi-continuous manufacturing of PLGA/PEG-PLGA microspheres
por: Anwar, Arfidin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v7c3on79t2sp7f8b9lnmpraurp