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Tumor-associated macrophage derived IL-6 enriches cancer stem cell population and promotes breast tumor progression via Stat-3 pathway

BACKGROUND: Cancer stem cells (CSCs) play crucial role in tumor progression, drug resistance and relapse in various cancers. CSC niche is comprised of various stromal cell types including Tumor-associated macrophages (TAMs). Extrinsic ques derived from these cells help in maintenance of CSC phenotyp...

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Detalles Bibliográficos
Autores principales: Radharani, N. N. V., Yadav, Amit S., Nimma, Ramakrishna, Kumar, T. V. Santosh, Bulbule, Anuradha, Chanukuppa, Venkatesh, Kumar, Dhiraj, Patnaik, Srinivas, Rapole, Srikanth, Kundu, Gopal C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932105/
https://www.ncbi.nlm.nih.gov/pubmed/35300689
http://dx.doi.org/10.1186/s12935-022-02527-9