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Exosomal microRNA-140-3p from human umbilical cord mesenchymal stem cells attenuates joint injury of rats with rheumatoid arthritis by silencing SGK1

OBJECTIVE: Over the years, microRNAs (miRNAs) have been involved in the pathogenesis of rheumatoid arthritis (RA). We aim to investigate the role of human umbilical cord mesenchymal stem cells (HUCMSCs)-derived exosomal miR-140-3p in RA development. METHODS: Exosomes(exo) were isolated from human um...

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Detalles Bibliográficos
Autores principales: Huang, Yijiang, Chen, Liang, Chen, Daosen, Fan, Pei, Yu, Huachen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932126/
https://www.ncbi.nlm.nih.gov/pubmed/35303795
http://dx.doi.org/10.1186/s10020-022-00451-2