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ATTR Epidemiology, Genetics, and Prognostic Factors

Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed disease and an underestimated cause of both heart failure and conduction abnormalities. It is characterized by pathologic accumulation of extracellular protein arising from unstable transthyretin (TTR) tetramers, which dissociate in...

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Detalles Bibliográficos
Autores principales: Obi, Chukwuemeka A., Mostertz, William C., Griffin, Jan M., Judge, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Houston Methodist DeBakey Heart & Vascular Center 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932385/
https://www.ncbi.nlm.nih.gov/pubmed/35414855
http://dx.doi.org/10.14797/mdcvj.1066