Latent TGFβ complexes are transglutaminase cross-linked to fibrillin to facilitate TGFβ activation

TGFβ superfamily members are potent growth factors in the extracellular matrix with essential roles in all aspects of cellular behaviour. Latent TGFβ binding proteins (LTBPs) are co-expressed with TGFβ, essential for correct folding and secretion of the growth factor, to form large latent complexes....

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Detalles Bibliográficos
Autores principales: Lockhart-Cairns, Michael P., Cain, Stuart A., Dajani, Rana, Steer, Ruth, Thomson, Jennifer, Alanazi, Yasmene F., Kielty, Cay M., Baldock, Clair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932414/
https://www.ncbi.nlm.nih.gov/pubmed/35122964
http://dx.doi.org/10.1016/j.matbio.2022.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932414/
https://www.ncbi.nlm.nih.gov/pubmed/35122964
http://dx.doi.org/10.1016/j.matbio.2022.01.005

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