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Latent TGFβ complexes are transglutaminase cross-linked to fibrillin to facilitate TGFβ activation
TGFβ superfamily members are potent growth factors in the extracellular matrix with essential roles in all aspects of cellular behaviour. Latent TGFβ binding proteins (LTBPs) are co-expressed with TGFβ, essential for correct folding and secretion of the growth factor, to form large latent complexes....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932414/ https://www.ncbi.nlm.nih.gov/pubmed/35122964 http://dx.doi.org/10.1016/j.matbio.2022.01.005 |