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Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage
Nuclear pore complexes (NPCs) discriminate nonspecific macromolecules from importin and exportin receptors, collectively termed “karyopherins” (Kaps), that mediate nucleocytoplasmic transport. This selective barrier function is attributed to the behavior of intrinsically disordered phenylalanine-gly...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932525/ https://www.ncbi.nlm.nih.gov/pubmed/35089308 http://dx.doi.org/10.1083/jcb.202108107 |