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Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage

Nuclear pore complexes (NPCs) discriminate nonspecific macromolecules from importin and exportin receptors, collectively termed “karyopherins” (Kaps), that mediate nucleocytoplasmic transport. This selective barrier function is attributed to the behavior of intrinsically disordered phenylalanine-gly...

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Detalles Bibliográficos
Autores principales:	Kalita, Joanna, Kapinos, Larisa E., Zheng, Tiantian, Rencurel, Chantal, Zilman, Anton, Lim, Roderick Y.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932525/ https://www.ncbi.nlm.nih.gov/pubmed/35089308 http://dx.doi.org/10.1083/jcb.202108107

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