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A loop extrusion–independent mechanism contributes to condensin I–mediated chromosome shaping

Condensin I is a five-subunit protein complex that is central to mitotic chromosome assembly in eukaryotic cells. Despite recent progress, its molecular mechanisms of action remain to be fully elucidated. By using Xenopus egg extracts as a functional assay, we find that condensin I complexes harbori...

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Detalles Bibliográficos
Autores principales: Kinoshita, Kazuhisa, Tsubota, Yuko, Tane, Shoji, Aizawa, Yuuki, Sakata, Ryota, Takeuchi, Kozo, Shintomi, Keishi, Nishiyama, Tomoko, Hirano, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932526/
https://www.ncbi.nlm.nih.gov/pubmed/35045152
http://dx.doi.org/10.1083/jcb.202109016