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Germinal center derived B cell memory without T cells

Liu et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20210527) in this issue show that T cell–independent germinal centers (GCs) can produce long-lived memory and plasma cell output. This may help explain how polysaccharide antigens provide long-term protection.

Detalles Bibliográficos
Autores principales: Zhang, Yang, Toellner, Kai-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932542/
https://www.ncbi.nlm.nih.gov/pubmed/35171242
http://dx.doi.org/10.1084/jem.20220012