THUNDER: A reference-free deconvolution method to infer cell type proportions from bulk Hi-C data

Hi-C data provide population averaged estimates of three-dimensional chromatin contacts across cell types and states in bulk samples. Effective analysis of Hi-C data entails controlling for the potential confounding factor of differential cell type proportions across heterogeneous bulk samples. We p...

Descripción completa

Detalles Bibliográficos
Autores principales: Rowland, Bryce, Huh, Ruth, Hou, Zoey, Crowley, Cheynna, Wen, Jia, Shen, Yin, Hu, Ming, Giusti-Rodríguez, Paola, Sullivan, Patrick F., Li, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932604/
https://www.ncbi.nlm.nih.gov/pubmed/35259165
http://dx.doi.org/10.1371/journal.pgen.1010102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932604/
https://www.ncbi.nlm.nih.gov/pubmed/35259165
http://dx.doi.org/10.1371/journal.pgen.1010102

Ejemplares similares