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THUNDER: A reference-free deconvolution method to infer cell type proportions from bulk Hi-C data

Hi-C data provide population averaged estimates of three-dimensional chromatin contacts across cell types and states in bulk samples. Effective analysis of Hi-C data entails controlling for the potential confounding factor of differential cell type proportions across heterogeneous bulk samples. We p...

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Detalles Bibliográficos
Autores principales:	Rowland, Bryce, Huh, Ruth, Hou, Zoey, Crowley, Cheynna, Wen, Jia, Shen, Yin, Hu, Ming, Giusti-Rodríguez, Paola, Sullivan, Patrick F., Li, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932604/ https://www.ncbi.nlm.nih.gov/pubmed/35259165 http://dx.doi.org/10.1371/journal.pgen.1010102

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