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Piezo1 regulates the regenerative capacity of skeletal muscles via orchestration of stem cell morphological states

Muscle stem cells (MuSCs) are essential for tissue homeostasis and regeneration, but the potential contribution of MuSC morphology to in vivo function remains unknown. Here, we demonstrate that quiescent MuSCs are morphologically heterogeneous and exhibit different patterns of cellular protrusions....

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Detalles Bibliográficos
Autores principales: Ma, Nuoying, Chen, Delia, Lee, Ji-Hyung, Kuri, Paola, Hernandez, Edward Blake, Kocan, Jacob, Mahmood, Hamd, Tichy, Elisia D., Rompolas, Panteleimon, Mourkioti, Foteini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932657/
https://www.ncbi.nlm.nih.gov/pubmed/35302846
http://dx.doi.org/10.1126/sciadv.abn0485