H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

Activation of interferon genes constitutes an important anticancer pathway able to restrict proliferation of cancer cells. Here, we demonstrate that the H3K9me3 histone methyltransferase (HMT) suppressor of variegation 3–9 homolog 1 (SUV39H1) is required for the proliferation of acute myeloid leukem...

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Detalles Bibliográficos
Autores principales: Hansen, Anne Meldgaard, Ge, Ying, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, Janus Schou, Kalvisa, Adrija, Tapia, Marta Cecylia, Gordon, Sandra, Ambri, Francesca, Bagger, Frederik Otzen, Pandey, Deo, Helin, Kristian, Porse, Bo Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932663/
https://www.ncbi.nlm.nih.gov/pubmed/35302840
http://dx.doi.org/10.1126/sciadv.abf8627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932663/
https://www.ncbi.nlm.nih.gov/pubmed/35302840
http://dx.doi.org/10.1126/sciadv.abf8627

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