ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers

RAF kinases are highly conserved serine/threonine kinases, and among the three RAF isoforms (ARAF, BRAF, and CRAF), the pathophysiological relevance of ARAF is not well defined. Here, we show that patients with lung cancer exhibit low expression of ARAF, which is associated with lymph node metastasi...

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Detalles Bibliográficos
Autores principales: Mooz, Juliane, Riegel, Kristina, PS, Hari, Sadanandam, Anguraj, Marini, Federico, Klein, Matthias, Werner, Ulrike, Roth, Wilfried, Wilken-Schmitz, Annett, Tegeder, Irmgard, Rajalingam, Krishnaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932670/
https://www.ncbi.nlm.nih.gov/pubmed/35302851
http://dx.doi.org/10.1126/sciadv.abk1538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932670/
https://www.ncbi.nlm.nih.gov/pubmed/35302851
http://dx.doi.org/10.1126/sciadv.abk1538

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