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How translational modeling in oncology needs to get the mechanism just right

Translational model‐based approaches have played a role in increasing success in the development of novel anticancer treatments. However, despite this, significant translational uncertainty remains from animal models to patients. Optimization of dose and scheduling (regimen) of drugs to maximize the...

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Detalles Bibliográficos
Autores principales: Yates, James W. T., Fairman, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932697/
https://www.ncbi.nlm.nih.gov/pubmed/34716976
http://dx.doi.org/10.1111/cts.13183