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Optimizing moxidectin dosing for Strongyloides stercoralis infections: Insights from pharmacometric modeling

Moxidectin is a frontrunner drug candidate in the treatment of strongyloidiasis. A dose of 8 mg is recommended to treat this indication, which shows a reasonably good efficacy and tolerability profile. Yet, owing to the unique life cycle of Strongyloides stercoralis (S. stercoralis) that entails int...

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Detalles Bibliográficos
Autores principales: Hofmann, Daniela, Smit, Cornelis, Sayasone, Somphou, Pfister, Marc, Keiser, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932710/
https://www.ncbi.nlm.nih.gov/pubmed/34889057
http://dx.doi.org/10.1111/cts.13189