Influence of CYP2D6 metabolizer status on ondansetron efficacy in pediatric patients undergoing hematopoietic stem cell transplantation: A case series

Chemotherapy‐induced nausea and vomiting (CINV) is commonly experienced by patients receiving antineoplastic agents prior to hemopoietic stem cell transplant (HSCT). Ondansetron, a 5‐HT3 antagonist metabolized by CYP2D6, is an antiemetic prescribed to treat short‐term CINV, but some patients still e...

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Detalles Bibliográficos
Autores principales: Edwards, Andrea, Teusink‐Cross, Ashley, Martin, Lisa J., Prows, Cynthia A., Mehta, Parinda A., Ramsey, Laura B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932713/
https://www.ncbi.nlm.nih.gov/pubmed/34670017
http://dx.doi.org/10.1111/cts.13171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932713/
https://www.ncbi.nlm.nih.gov/pubmed/34670017
http://dx.doi.org/10.1111/cts.13171

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