Pharmacokinetics of bempedoic acid in patients with renal impairment

Bempedoic acid is an ATP citrate lyase inhibitor approved for the treatment of hypercholesterolemia. The objective of this phase I study was to assess the pharmacokinetics (PKs) and safety of bempedoic acid in 24 subjects with normal renal function or mild, moderate, or severe renal impairment. All...

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Detalles Bibliográficos
Autores principales: Amore, Benny M., Sasiela, William J., Ries, Daniel K., Tresh, Perry, Emery, Maurice G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932715/
https://www.ncbi.nlm.nih.gov/pubmed/34800002
http://dx.doi.org/10.1111/cts.13202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932715/
https://www.ncbi.nlm.nih.gov/pubmed/34800002
http://dx.doi.org/10.1111/cts.13202

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