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Pharmacokinetics of bempedoic acid in patients with renal impairment

Bempedoic acid is an ATP citrate lyase inhibitor approved for the treatment of hypercholesterolemia. The objective of this phase I study was to assess the pharmacokinetics (PKs) and safety of bempedoic acid in 24 subjects with normal renal function or mild, moderate, or severe renal impairment. All...

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Detalles Bibliográficos
Autores principales:	Amore, Benny M., Sasiela, William J., Ries, Daniel K., Tresh, Perry, Emery, Maurice G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932715/ https://www.ncbi.nlm.nih.gov/pubmed/34800002 http://dx.doi.org/10.1111/cts.13202

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