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The Fab portion of immunoglobulin G has sites in the CL domain that interact with Fc gamma receptor IIIa

The interaction between IgG and Fc gamma receptor IIIa (FcγRIIIa) is essential for mediating immune responses. Recent studies have shown that the antigen binding fragment (Fab) and Fc are involved in IgG-FcγRIII interactions. Here, we conducted bio-layer interferometry (BLI) and isothermal titration...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yuki, Wakaizumi, Natsumi, Irisa, Mine, Maruno, Takahiro, Shimada, Mari, Shintani, Koya, Nishiumi, Haruka, Yogo, Rina, Yanaka, Saeko, Higo, Daisuke, Torisu, Tetsuo, Kato, Koichi, Uchiyama, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932917/
https://www.ncbi.nlm.nih.gov/pubmed/35291930
http://dx.doi.org/10.1080/19420862.2022.2038531