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QPCTL regulates macrophage and monocyte abundance and inflammatory signatures in the tumor microenvironment

The enzyme glutaminyl-peptide cyclotransferase-like protein (QPCTL) catalyzes the formation of pyroglutamate residues at the NH(2)-terminus of proteins, thereby influencing their biological properties. A number of studies have implicated QPCTL in the regulation of chemokine stability. Furthermore, Q...

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Detalles Bibliográficos
Autores principales: Bresser, Kaspar, Logtenberg, Meike E. W., Toebes, Mireille, Proost, Natalie, Sprengers, Justin, Siteur, Bjorn, Boeije, Manon, Kroese, Lona J., Schumacher, Ton N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932921/
https://www.ncbi.nlm.nih.gov/pubmed/35309731
http://dx.doi.org/10.1080/2162402X.2022.2049486