CLEC5a-directed bispecific antibody for effective cellular phagocytosis

While antibody-dependent cellular phagocytosis mediated by activating Fcγ receptor is a key mechanism underlying many antibody drugs, their full therapeutic activities can be restricted by the inhibitory Fcγ receptor IIB (FcγRIIB). Here, we describe a bispecific antibody approach that harnesses phag...

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Detalles Bibliográficos
Autores principales: Kedage, Vivekananda, Ellerman, Diego, Fei, Mingjian, Liang, Wei-Ching, Zhang, Gu, Cheng, Eric, Zhang, Juan, Chen, Yongmei, Huang, Haochu, Lee, Wyne P., Wu, Yan, Yan, Minhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932924/
https://www.ncbi.nlm.nih.gov/pubmed/35293277
http://dx.doi.org/10.1080/19420862.2022.2040083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932924/
https://www.ncbi.nlm.nih.gov/pubmed/35293277
http://dx.doi.org/10.1080/19420862.2022.2040083

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