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CLEC5a-directed bispecific antibody for effective cellular phagocytosis

While antibody-dependent cellular phagocytosis mediated by activating Fcγ receptor is a key mechanism underlying many antibody drugs, their full therapeutic activities can be restricted by the inhibitory Fcγ receptor IIB (FcγRIIB). Here, we describe a bispecific antibody approach that harnesses phag...

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Detalles Bibliográficos
Autores principales:	Kedage, Vivekananda, Ellerman, Diego, Fei, Mingjian, Liang, Wei-Ching, Zhang, Gu, Cheng, Eric, Zhang, Juan, Chen, Yongmei, Huang, Haochu, Lee, Wyne P., Wu, Yan, Yan, Minhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932924/ https://www.ncbi.nlm.nih.gov/pubmed/35293277 http://dx.doi.org/10.1080/19420862.2022.2040083

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