A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation

Polycystin-1 (PC-1, PKD1), a receptor-like protein expressed by the Pkd1 gene, is present in a wide variety of cell types, but its cellular location, signaling mechanisms, and physiological functions are poorly understood. Here, by studying tamoxifen-inducible, endothelial cell (EC)-specific Pkd1 kn...

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Detalles Bibliográficos
Autores principales: MacKay, Charles E, Floen, Miranda, Leo, M Dennis, Hasan, Raquibul, Garrud, Tessa AC, Fernández-Peña, Carlos, Singh, Purnima, Malik, Kafait U, Jaggar, Jonathan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933003/
https://www.ncbi.nlm.nih.gov/pubmed/35229718
http://dx.doi.org/10.7554/eLife.74765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933003/
https://www.ncbi.nlm.nih.gov/pubmed/35229718
http://dx.doi.org/10.7554/eLife.74765

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