Novel insights from a multiomics dissection of the Hayflick limit

The process wherein dividing cells exhaust proliferative capacity and enter into replicative senescence has become a prominent model for cellular aging in vitro. Despite decades of study, this cellular state is not fully understood in culture and even much less so during aging. Here, we revisit Leon...

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Detalles Bibliográficos
Autores principales: Chan, Michelle, Yuan, Han, Soifer, Ilya, Maile, Tobias M, Wang, Rebecca Y, Ireland, Andrea, O'Brien, Jonathon J, Goudeau, Jérôme, Chan, Leanne JG, Vijay, Twaritha, Freund, Adam, Kenyon, Cynthia, Bennett, Bryson D, McAllister, Fiona E, Kelley, David R, Roy, Margaret, Cohen, Robert L, Levinson, Arthur D, Botstein, David, Hendrickson, David G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933007/
https://www.ncbi.nlm.nih.gov/pubmed/35119359
http://dx.doi.org/10.7554/eLife.70283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933007/
https://www.ncbi.nlm.nih.gov/pubmed/35119359
http://dx.doi.org/10.7554/eLife.70283

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