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Initial Angiotensin Receptor Blocker Response in Young Marfan Patients Decreases After 3 Years of Treatment

Marfan syndrome is caused by mutations of the fibrillin-1 gene, which weakens the connective tissue integrity. Since 2003, bioavailability regulations of TGF-ß through fibrillin alterations have been presumed of being the culprit mechanisms for aortic aneurysm development. We present the analysis of...

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Detalles Bibliográficos
Autores principales: Pees, Christiane, Heno, Julian, Michel-Behnke, Ina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933348/
https://www.ncbi.nlm.nih.gov/pubmed/34757469
http://dx.doi.org/10.1007/s00246-021-02761-4