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Initial Angiotensin Receptor Blocker Response in Young Marfan Patients Decreases After 3 Years of Treatment
Marfan syndrome is caused by mutations of the fibrillin-1 gene, which weakens the connective tissue integrity. Since 2003, bioavailability regulations of TGF-ß through fibrillin alterations have been presumed of being the culprit mechanisms for aortic aneurysm development. We present the analysis of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933348/ https://www.ncbi.nlm.nih.gov/pubmed/34757469 http://dx.doi.org/10.1007/s00246-021-02761-4 |